A young boy wheel chair bound, brought with complaints of multiple nodular swelling, bone pain and recurrent osteomyelitis. He had many antibiotics and local surgeries for last 07 yrs. For some reason he had splenectomy in the past.
Bone marrow was asked to confirm the suspicion of gaucher disease. Report showed PAS positive lipid laden gaucher cells. Glucocerebrosidase deficiency confirmed from Mayo clinic lab.
As treatment includes enzyme replacement and is costly affair, alternative was sought.
Resveratrol is well known for its beneficial metabolic and antiapoptic effect. It is also a good plant source of enzyme glucocerebrosidase.
Resveratrol 500mg twice daily completely resolved the disease and boy was up and about after 03 months. Nearly 02 year of followup and boy is doing well.