SEVERE DEPRESSION
A young lady with severe depression , aggression and suicidal ideation.
Had treatment with many psychiatrists for last 4-5 years. Combination of various antidepressants and ECT done with no relief.
Brought in with low mood ,refusal to undergo treatment from psychiatrist and suicidal thoughts.
Left with few choices, ketamine was tried.
Ketamine is NMDA receptor agonist. It has rapid antidepressant effect which last for several weeks. For this low dosage is used and it can be given orally. A 50 – 100 mg single oral dose at night usually gives a good result.
Patient was advised single dose with a repeat dose at 04 weeks. Patient showed a remarkable recovery.
At present she is on regular SSRI therapy, with no suicidal ideation and willing to change her life for better.